Article
Lines is required for normal operation of Wingless, Hedgehog and Notch pathways during wing development.
Development (Cambridge, England) - 1 Apr 2009
Benítez Elvira, Bray Sarah J, Rodriguez Isabel, Guerrero Isabel
Abstract excerpt
The regulatory Lines/Drumstick/Bowl gene network is implicated in the integration of patterning information at several stages during development. Here, we show that during Drosophila wing development, Lines prevents Bowl accumulation in the wing primordium, confining its expression to the peripodial epithelium. In cells that lack lines or over-expressing Drumstick, Bowl stabilization is responsible for...
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