Article
Plasma homocysteine thiolactone adducts associated with risk of coronary heart disease.
Clinica chimica acta; international journal of clinical chemistry - 1 Feb 2006
Yang Xu, Gao Yan, Zhou Jin, Zhen Yisong, Yang Yuejin, Wang Jizheng, Song Li, Liu Yuqing, Xu Haiyan, Chen Zaijia, Hui Rutai
Abstract excerpt
BACKGROUND: Homocysteine thiolactone adducts have been proposed as the culprit of homocysteine related cardiovascular diseases. We studied the association of these adducts in plasma, and the gene polymorphism of paraoxonase-2 with coronary heart disease. METHODS: 254 patients and 308 controls were recruited for the study. Homocysteine thiolactone adducts were determined with ELISA. The codon 311 polymorphism of...
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