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Article

Association of the C677T MTHFR polymorphism with homocysteine, ox-LDL levels, and thiolactonase activities in the severity of coronary syndrome.

Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis - 1 Oct 2010

Koubaa Nadia, Nakbi Amel, Hammami Sonia, Mehri Sounira, Attia Nabil, Ben Farhat Mohamed, Hammami Mohamed

Abstract excerpt

Coronary artery diseases (CAD) are influenced by multiple genes of modest effect as the methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism, related to MTHFR activity and total plasma homocysteine (tHcy) concentration. This study was designed to evaluate tHcy, oxidized low-density lipoprotein (LDL) (ox-LDL), high-sensibility C-reactive protein (Hs CRP) levels, and homocysteine thiolactonase...

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Topics

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Share to C-Reactive Protein
Share to Carboxylic Ester Hydrolases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Coronary Artery Disease

Share to Homocysteine

Share to Lipoproteins, LDL

Share to Methylenetetrahydrofolate Reductase (NADPH2)

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Source

Identifiers

PMID: 20530057
DOI: 10.1177/1076029610369798

Genes

MTHFR
CAD
CRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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