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Article

Regulation of Spo12 phosphorylation and its essential role in the FEAR network.

Current biology : CB - 24 Mar 2009

Tomson Brett N, Rahal Rami, Reiser Vladimír, Monje-Casas Fernando, Mekhail Karim, Moazed Danesh, Amon Angelika

Abstract excerpt

BACKGROUND: In budding yeast, the protein phosphatase Cdc14 coordinates late mitotic events and triggers exit from mitosis. During early anaphase, Cdc14 is activated by the FEAR network, but how signaling through the FEAR network occurs is poorly understood. RESULTS: We find that the FEAR network component Spo12 is phosphorylated on S118. This phosphorylation is essential for Spo12 function and is restricted to...

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Identifiers

PMID: 19268588
DOI: 10.1016/j.cub.2009.02.024
PMCID: PMC2692463

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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