Article
The Mediterranean diet protects against waist circumference enlargement in 12Ala carriers for the PPARgamma gene: 2 years' follow-up of 774 subjects at high cardiovascular risk.
The British journal of nutrition - 1 Sept 2009
Razquin Cristina, Alfredo Martinez J, Martinez-Gonzalez Miguel A, Corella Dolores, Santos José Manuel, Marti Amelia
Abstract excerpt
The PPARgamma gene regulates insulin sensitivity and adipogenesis. The Pro12Ala polymorphism of this gene has been related to fat accumulation. Our aim was to analyse the effects of a 2-year nutritional intervention with Mediterranean-style diets on adiposity in high-cardiovascular risk patients depending on the Pro12Ala polymorphism of the PPARgamma gene. The population consisted of a substudy (774 high-risk...
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