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Pro12Ala Polymorphism of the <i>PPARγ2</i> Gene Interacts With a Mediterranean Diet to Prevent Telomere Shortening in the PREDIMED-NAVARRA Randomized Trial

19 Nov 2014

Abstract excerpt

BACKGROUND: The gene variant Pro/Ala (rs1801282) in the PPARγ2 has been associated with lower cardiovascular risk and greater benefit from lifestyle interventions. This polymorphism also seems to be associated with longer lifespan, but no information on telomere length (TL) is available. Our aim was to study the association between the Ala allele and changes in TL in high cardiovascular risk subjects and the...

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PMID: 25406242
DOI: 10.1161/circgenetics.114.000635

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