Article
Alcohol intake modulates the genetic association between HDL cholesterol and the PPARgamma2 Pro12Ala polymorphism.
Journal of lipid research - 1 May 2005
Brand-Herrmann Stefan-Martin, Kuznetsova Tatiana, Wiechert Andreas, Stolarz Katarzyna, Tikhonoff Valerie, Schmidt-Petersen Klaus, Telgmann Ralph, Casiglia Edoardo, Wang Ji-Guang, Thijs Lutgarde, Staessen Jan A, Brand Eva
Abstract excerpt
The peroxisome proliferator-activated receptor gamma (PPARgamma) Pro12Ala polymorphism affects plasma lipids, but to what extent alcohol intake interferes with this association remains unknown. We randomly recruited 251 nuclear families (433 parents and 493 offspring) in the framework of the European Project on Genes in Hypertension study and genotyped 926 participants in whom all serum lipid variables and...
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