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Article

B7 costimulation is critical for host control of chronic Mycobacterium tuberculosis infection.

Journal of immunology (Baltimore, Md. : 1950) - 15 Mar 2009

Bhatt Kamlesh, Uzelac Aleksandra, Mathur Sanjeev, McBride Amanda, Potian Julius, Salgame Padmini

Abstract excerpt

Although much is understood regarding the role of B7/CD28 family of costimulatory molecules in regulating host resistance in the context of several pathogens, analogous information with Mycobacterium tuberculosis is lacking. To address the requirements of B7-mediated costimulation in host resistance against tuberculosis, mice deficient in both B7.1 and B7.2 (B7DKO) were aerosol infected with M. tuberculosis...

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Source

Identifiers

PMID: 19265158
DOI: 10.4049/jimmunol.0802996

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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