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Chikungunya triggers an autophagic process which promotes viral replication

8 Sept 2011

Abstract excerpt

BACKGROUND: Chikungunya Virus (ChikV) surprised by a massive re-emerging outbreak in Indian Ocean in 2006, reaching Europe in 2007 and exhibited exceptional severe physiopathology in infants and elderly patients. In this context, it is important to analyze the innate immune host responses triggered against ChikV. Autophagy has been shown to be an important component of the innate immune response and is involved...

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PMID: 21902836
DOI: 10.1186/1743-422x-8-432

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