Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transgenic mouse models of Parkinson's disease and Huntington's disease.

CNS & neurological disorders drug targets - 1 Aug 2010

Skaper Stephen D, Giusti Pietro

Abstract excerpt

Parkinson's disease (PD) is a chronic progressive neurodegenerative movement disorder characterized by a profound and selective loss of nigrostriatal dopaminergic neurons. Another neurodegenerative disorder, Huntington's disease (HD), is characterized by striking movement abnormalities and the loss of medium-sized spiny neurons in the striatum. Current medications only provide symptomatic relief and fail to halt...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disease Models, Animal
Share to Gene Knock-In Techniques
Share to Genes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Huntington Disease

Share to Mice, Transgenic

Share to Mutation

Share to Parkinson Disease

Source

Identifiers

PMID: 20522011
DOI: 10.2174/187152710791556186

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transgenic mouse models of Parkinson's disease and Huntington's disease.PMID 20522011Read ↗

Mouse Models of Huntington's Disease.Semantic proximity Read ↗

The use of transgenic and knock-in mice to study Huntington's disease.Semantic proximity Read ↗

Transgenic animal models for study of the pathogenesis of Huntington's disease and therapy.Semantic proximity Read ↗

Genetic Neurodegenerative Diseases: The Human Illness and Transgenic ModelsSemantic proximity Read ↗

Strategies for Optimizing Genetic Mouse Models to Enhance the Understanding of Parkinson’s DiseaseSemantic proximity Read ↗

Genetic Animal Models of Parkinson's DiseaseSemantic proximity Read ↗

Transgenic mouse models of neurodegenerative disease: opportunities for therapeutic development.Semantic proximity Read ↗

Transgenic rodent models of Parkinson's disease.Semantic proximity Read ↗

Models of Parkinson's diseaseSemantic proximity Read ↗

Animal models of Parkinson's disease: bridging the gap between disease hallmarks and research questions.Semantic proximity Read ↗

Classic and evolving animal models in Parkinson's disease.Semantic proximity Read ↗

New Developments in Genetic rat models of Parkinson's Disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.