Article
Hypermethylation of the breast cancer-associated gene 1 promoter does not predict cytologic atypia or correlate with surrogate end points of breast cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2007
Bean Gregory R, Ibarra Drendall Catherine, Goldenberg Vanessa K, Baker Joseph C, Troch Michelle M, Paisie Carolyn, Wilke Lee G, Yee Lisa, Marcom Paul K, Kimler Bruce F, Fabian Carol J, Zalles Carola M, Broadwater Gloria, Scott Victoria, Seewaldt Victoria L
Abstract excerpt
Mutation of the breast cancer-associated gene 1 (BRCA1) plays an important role in familial breast cancer. Although hypermethylation of the BRCA1 promoter has been observed in sporadic breast cancer, its exact role in breast cancer initiation and association with breast cancer risk is unknown. Th...
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