Article
Improved outcome of hematopoietic SCT in patients with homozygous gene variant of Toll-like receptor 9.
Bone marrow transplantation - 1 Sept 2009
Elmaagacli A H, Koldehoff M, Beelen D W
Abstract excerpt
Toll-like receptor 9 (TLR9) is part of the innate immune system, which is activated by CpG oligonucleotides (ODNs) and produces potent Th1-type innate and adaptive immune responses. It is reported that TLR9 gene variants, T1486C and T1237C, are associated with a reduced TLR9 expression compared w...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
