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Article

Novel role of RanBP9 in BACE1 processing of amyloid precursor protein and amyloid beta peptide generation.

The Journal of biological chemistry - 1 May 2009

Lakshmana Madepalli K, Yoon Il-Sang, Chen Eunice, Bianchi Elizabetta, Koo Edward H, Kang David E

Abstract excerpt

Accumulation of the amyloid beta (Abeta) peptide derived from the proteolytic processing of amyloid precursor protein (APP) is the defining pathological hallmark of Alzheimer disease. We previously demonstrated that the C-terminal 37 amino acids of lipoprotein receptor-related protein (LRP) robus...

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Identifiers

PMID: 19251705
DOI: 10.1074/jbc.M807345200
PMCID: PMC2673255

Genes

APP
BACE1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19251705-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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