Article
Membrane topology of the N-terminus of the Escherichia coli FtsK division protein.
FEBS letters - 28 Jul 2000
Dorazi R, Dewar S J
Abstract excerpt
The Escherichia coli FtsK protein targets the septum, is essential for cell division and may play a role in DNA partitioning. Computer modelling suggests that the first 180 amino acids of the protein are embedded in the cytoplasmic membrane by up to six transmembrane domains. We demonstrate, using gene fusions, that the N-terminus contains four transmembrane helices that link two periplasmic domains. The first...
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