Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High differentiation among eight villages in a secluded area of Sardinia revealed by genome-wide high density SNPs analysis.

PloS one - 1 Jan 2009

Pistis Giorgio, Piras Ignazio, Pirastu Nicola, Persico Ivana, Sassu Alessandro, Picciau Andrea, Prodi Dionigio, Fraumene Cristina, Mocci Evelina, Manias Maria Teresa, Atzeni Rossano, Cosso Massimiliano, Pirastu Mario, Angius Andrea

Abstract excerpt

To better design association studies for complex traits in isolated populations it's important to understand how history and isolation moulded the genetic features of different communities. Population isolates should not "a priori" be considered homogeneous, even if the communities are not distant and part of a small region. We studied a particular area of Sardinia called Ogliastra, characterized by the presence...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetics, Population
Share to Genome, Human

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Linkage Disequilibrium

Share to Polymorphism, Single Nucleotide

Share to Rural Population

Source

Open in PubMed Open full text

Identifiers

PMID: 19247500
DOI: 10.1371/journal.pone.0004654
PMCID: PMC2646134

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High differentiation among eight villages in a secluded area of Sardinia revealed by genome-wide high density SNPs analysis.PMID 19247500Read ↗

Not all isolates are equal: linkage disequilibrium analysis on Xq13.3 reveals different patterns in Sardinian sub-populations.Semantic proximity Read ↗

Dissecting the genetic make-up of North-East Sardinia using a large set of haploid and autosomal markers.Semantic proximity Read ↗

History, geography and population structure influence the distribution and heritability of blood and anthropometric quantitative traits in nine Sardinian genetic isolates.Semantic proximity Read ↗

Patterns of linkage disequilibrium between SNPs in a Sardinian population isolate and the selection of markers for association studies.Semantic proximity Read ↗

Archival, demographic and genetic studies define a Sardinian sub-isolate as a suitable model for mapping complex traits.Semantic proximity Read ↗

High resolution analysis and phylogenetic network construction using complete mtDNA sequences in sardinian genetic isolates.Semantic proximity Read ↗

Striking differentiation of sub-populations within a genetically homogeneous isolate (Ogliastra) in Sardinia as revealed by mtDNA analysis.Semantic proximity Read ↗

Genome-wide scan with nearly 700,000 SNPs in two Sardinian sub-populations suggests some regions as candidate targets for positive selection.Semantic proximity Read ↗

Population history of the Sardinian people inferred from whole-genome sequencingSemantic proximity Read ↗

Genetic characterization of northeastern Italian population isolates in the context of broader European genetic diversity.Semantic proximity Read ↗

Extent of linkage disequilibrium in a Sardinian sub-isolate: sampling and methodological considerations.Semantic proximity Read ↗

Sardinians genetic background explained by runs of homozygosity and genomic regions under positive selection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.