Article
Archival, demographic and genetic studies define a Sardinian sub-isolate as a suitable model for mapping complex traits.
Human genetics - 1 Aug 2001
Angius A, Melis P M, Morelli L, Petretto E, Casu G, Maestrale G B, Fraumene C, Bebbere D, Forabosco P, Pirastu M
Abstract excerpt
Genetic isolates represent exceptional resources for the mapping of complex traits but not all isolates are similar. We have selected a genetic and cultural isolate, the village of Talana from an isolated area of Sardinia, and propose that this population is suitable for the mapping of complex traits. A wealth of historical and archive data allowed the reconstruction of the demographic and genealogical history of...
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