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Article

Dissecting the genetic make-up of North-East Sardinia using a large set of haploid and autosomal markers.

European journal of human genetics : EJHG - 1 Sept 2012

Pardo Luba M, Piras Giovanna, Asproni Rosanna, van der Gaag Kristiaan J, Gabbas Attilio, Ruiz-Linares Andres, de Knijff Peter, Monne Maria, Rizzu Patrizia, Heutink Peter

Abstract excerpt

Sardinia has been used for genetic studies because of its historical isolation, genetic homogeneity and increased prevalence of certain rare diseases. Controversy remains concerning the genetic substructure and the extent of genetic homogeneity, which has implications for the design of genome-wide association studies (GWAS). We revisited this issue by examining the genetic make-up of a sample from North-East...

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PMID: 22378280
DOI: 10.1038/ejhg.2012.22
PMCID: PMC3421114

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Source receipt: pubmed, retrieved 7 Sept 2026.

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