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Article

A temporal threshold for formaldehyde crosslinking and fixation.

PloS one - 1 Jan 2009

Schmiedeberg Lars, Skene Pete, Deaton Aimée, Bird Adrian

Abstract excerpt

BACKGROUND: Formaldehyde crosslinking is in widespread use as a biological fixative for microscopy and molecular biology. An assumption behind its use is that most biologically meaningful interactions are preserved by crosslinking, but the minimum length of time required for an interaction to bec...

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Identifiers

PMID: 19247482
DOI: 10.1371/journal.pone.0004636
PMCID: PMC2645674

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19247482-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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