Article
Cross-linking of actin filaments by myosin II is a major contributor to cortical integrity and cell motility in restrictive environments.
Journal of cell science - 15 Sept 2003
Laevsky Gary, Knecht David A
Abstract excerpt
Cells are frequently required to move in a local environment that physically restricts locomotion, such as during extravasation or metastatic invasion. In order to model these events, we have developed an assay in which vegetative Dictyostelium amoebae undergo chemotaxis under a layer of agarose toward a source of folic acid [Laevsky, G. and Knecht, D. A. (2001). Biotechniques 31, 1140-1149]. As the concentration...
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