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Article

The sensor kinase PhoQ mediates virulence in Pseudomonas aeruginosa.

Microbiology (Reading, England) - 1 Mar 2009

Gooderham W James, Gellatly Shaan L, Sanschagrin François, McPhee Joseph B, Bains Manjeet, Cosseau Celine, Levesque Roger C, Hancock Robert E W

Abstract excerpt

Pseudomonas aeruginosa is a ubiquitous environmental Gram-negative bacterium that is also a major opportunistic human pathogen in nosocomial infections and cystic fibrosis chronic lung infections. PhoP-PhoQ is a two-component regulatory system that has been identified as essential for virulence and cationic antimicrobial peptide resistance in several other Gram-negative bacteria. This study demonstrated that...

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PMID: 19246741
DOI: 10.1099/mic.0.024554-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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