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Article

Relationship between TNF-α -1031T/C gene polymorphism, plasma level of TNF-α, and risk of cachexia in head and neck cancer patients.

Journal of cancer research and clinical oncology - 1 Aug 2018

Powrózek Tomasz, Mlak Radosław, Brzozowska Anna, Mazurek Marcin, Gołębiowski Paweł, Małecka-Massalska Teresa

Abstract excerpt

BACKGROUND: Malnutrition and cachexia are frequent among head and neck cancer (HNC) patients and these syndromes are associated with both poor quality of life and unfavorable disease prognosis. Unfortunately, there are still no established biomarkers that could predict the development of cachexia. Among potential molecular alterations related to cancer cachexia, there are single-nucleotide polymorphisms (SNPs)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29802455
DOI: 10.1007/s00432-018-2679-4
PMCID: PMC6061036

Genes

TNF

Provenance

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