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Polymorphisms in the FAS and FASL genes and risk of lung cancer in a Korean population.

Lung cancer (Amsterdam, Netherlands) - 1 Dec 2006

Park Sun Ha, Choi Jin Eun, Kim Eun Jin, Jang Jin Sung, Lee Won Kee, Cha Sung Ick, Kim Chang Ho, Kam Sin, Kim Dong Sun, Park Rang-Woon, Kim Young-Chul, Han Sung Beom, Jung Tae Hoon, Park Jae Yong

Abstract excerpt

BACKGROUND: The FAS and FASL system play an important role in regulating extrinsic apoptotic pathway and inappropriate regulation of this signaling pathway contributes to lung tumorigenesis. Polymorphisms in the promoter region of the FAS (-1377G>A and -670A>G) and FASL (-844C>T) have been shown to alter the transcriptional activities of these genes. In order to evaluate the contribution of these polymorphisms to...

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Identifiers

PMID: 17014925
DOI: 10.1016/j.lungcan.2006.09.002

Genes

FAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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