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Article

Contribution of impaired myocardial insulin signaling to mitochondrial dysfunction and oxidative stress in the heart.

Circulation - 10 Mar 2009

Boudina Sihem, Bugger Heiko, Sena Sandra, O'Neill Brian T, Zaha Vlad G, Ilkun Olesya, Wright Jordan J, Mazumder Pradip K, Palfreyman Eric, Tidwell Timothy J, Theobald Heather, Khalimonchuk Oleh, Wayment Benjamin, Sheng Xiaoming, Rodnick Kenneth J, Centini Ryan, Chen Dong, Litwin Sheldon E, Weimer Bart E, Abel E Dale

Abstract excerpt

BACKGROUND: Diabetes-associated cardiac dysfunction is associated with mitochondrial dysfunction and oxidative stress, which may contribute to left ventricular dysfunction. The contribution of altered myocardial insulin action, independent of associated changes in systemic metabolism, is incomple...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19237663
DOI: 10.1161/CIRCULATIONAHA.108.792101
PMCID: PMC2739097

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19237663-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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