Article
Allelic frequencies of HPA-1 to 5 human platelet antigens in patients infected with hepatitis C virus.
Journal of medical virology - 1 Apr 2009
Verdichio-Moraes Camila Fernanda, Toralles-Pereira Cecília, Grotto Rejane Maria Tommasini, Silva Giovanni Faria, Pardini Maria Inês de Moura Campos
Abstract excerpt
Studies have suggested that hepatitis C virus (HCV) may infect not only hepatocytes but may also be carried by platelets. Platelets express more than 20 polymorphic antigenic determinants on their surface, which are called human platelet antigens (HPA). To determine the allele frequency of the HPA-1 to -5 in patients infected with HCV, blood samples were collected from 257 blood donors for the control group and...
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