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Article

Human platelet antigen genotype is associated with progression of fibrosis in chronic hepatitis C.

Journal of medical virology - 1 Jan 2012

Silva Giovanni Faria, Grotto Rejane Maria Tommasini, Verdichio-Moraes Camila Fernanda, Corvino Silvia Maria, Ferrasi Adriana Camargo, Silveira Liciana Vaz de Arruda, Pardini Maria Inês de Moura Campos

Abstract excerpt

Although progression of fibrosis in the chronic hepatitis C depends on environmental, viral, and host factors, genetic polymorphisms have been associated recently with this progression, including the expression of integrins, adhesion proteins. Some integrins expressed on the platelet membrane show polymorphic antigenic determinants called human platelet antigens (HPA), where the major ones are HPA-1, -3, -5. The...

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Share to Antigens, Human Platelet
Share to Disease Progression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis C, Chronic

Share to Liver Cirrhosis

Share to Polymorphism, Restriction Fragment Length

Share to Polymorphism, Single-Stranded Conformational

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Source

Identifiers

PMID: 22095535
DOI: 10.1002/jmv.22191

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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