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Article

High-level expression of the HIV-1 Pr55gag polyprotein in transgenic tobacco chloroplasts.

Planta - 1 Apr 2009

Scotti Nunzia, Alagna Fiammetta, Ferraiolo Enrico, Formisano Gelsomina, Sannino Lorenza, Buonaguro Luigi, De Stradis Angelo, Vitale Alessandro, Monti Luigi, Grillo Stefania, Buonaguro Franco M, Cardi Teodoro

Abstract excerpt

Plants have been recognized as a promising production platform for recombinant pharmaceutical proteins. The human immunodeficiency virus Gag (Pr55(gag)) structural polyprotein precursor is a prime candidate for developing a HIV-1 vaccine, but, so far, has been expressed at very low level in plants. The aim of this study was to investigate factors potentially involved in Pr55(gag) expression and increase protein...

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Share to gag Gene Products, Human Immunodeficiency Virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19234717
DOI: 10.1007/s00425-009-0898-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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