Article
Plastid expression of a double-pentameric vaccine candidate containing human papillomavirus-16 L1 antigen fused with LTB as adjuvant: transplastomic plants show pleiotropic phenotypes.
Plant biotechnology journal - 1 Aug 2011
Waheed Mohammad T, Thönes Nadja, Müller Martin, Hassan Syed W, Gottschamel Johanna, Lössl Elke, Kaul Hans-Peter, Lössl Andreas G
Abstract excerpt
Human papillomavirus (HPV) causes cervical cancer in women worldwide, which is currently prevented by vaccines based on virus-like particles (VLPs). However, these vaccines have certain limitations in their availability to developing countries, largely due to elevated costs. Concerning the highest burden of disease in resource-poor countries, development of an improved mucosal and cost-effective vaccine is a...
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