Article
High expression level of a foot and mouth disease virus epitope in tobacco transplastomic plants.
Planta - 1 Jan 2010
Lentz Ezequiel Matías, Segretin María Eugenia, Morgenfeld Mauro Miguel, Wirth Sonia Alejandra, Dus Santos María José, Mozgovoj Marina Valeria, Wigdorovitz Andrés, Bravo-Almonacid Fernando Félix
Abstract excerpt
Chloroplast transformation has an extraordinary potential for antigen production in plants because of the capacity to accumulate high levels of recombinant proteins and increased biosafety due to maternal plastid inheritance in most crops. In this article, we evaluate tobacco chloroplasts transformation for the production of a highly immunogenic epitope containing amino acid residues 135-160 of the structural...
Topics
- Animals
- Capsid Proteins
- Chloroplasts
- Epitopes
- Foot-and-Mouth Disease
- Foot-and-Mouth Disease Virus
- Genetic Vectors
- Glucuronidase
- Mice
- Phenotype
- Plant Proteins
- Plants, Genetically Modified
- Nicotiana
- Transformation, Genetic