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Article

Rapid dendritic cell mobilization to the large intestinal epithelium is associated with resistance to Trichuris muris infection.

Journal of immunology (Baltimore, Md. : 1950) - 1 Mar 2009

Cruickshank Sheena M, Deschoolmeester Matthew L, Svensson Marcus, Howell Gareth, Bazakou Aikaterini, Logunova Larisa, Little Matthew C, English Nicholas, Mack Matthias, Grencis Richard K, Else Kathryn J, Carding Simon R

Abstract excerpt

The large intestine is a major site of infection and disease, yet little is known about how immunity is initiated within this site and the role of dendritic cells (DCs) in this process. We used the well-established model of Trichuris muris infection to investigate the innate response of colonic DCs in mice that are inherently resistant or susceptible to infection. One day postinfection, there was a significant...

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Identifiers

PMID: 19234202
DOI: 10.4049/jimmunol.0802749
PMCID: PMC2671799

Genes

CCL20
CCL5
CCL2
CCL3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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