Rapid cytoskeleton remodelling in dendritic cells following invasion byToxoplasma gondiicoincides with the onset of a hypermigratory phenotype

Abstract excerpt

Host cell manipulation is an important feature of the obligate intracellular parasite Toxoplasma gondii. Recent reports have shown that the tachyzoite stages subvert dendritic cells (DC) as a conduit for dissemination (Trojan horse) during acute infection. To examine the cellular basis of these processes, we performed a detailed analysis of the early events following tachyzoite invasion of human monocyte-derived...

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