Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Long-range linkage on chromosome 6p of VEGF, FKBP5, HLA and TNF alleles associated with transplant rejection.

Molecular immunology - 1 Nov 2009

Chen Yan, Cicciarelli James, Pravica Vera, Hutchinson Ian V

Abstract excerpt

Polymorphisms in several genes on the short arm of chromosome 6 (6p), among them, VEGF, FKBP5, HLA-DR and TNF-alpha, have been associated with inflammation and transplant outcome, such as acute rejection. Independent segregation of these genes is unproven, so we investigated linkage between distant genes on 6p and the putative existence of evolutionarily conserved long-range 6p haplotypes. SNPs studied were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 6
Share to Graft Rejection
Share to HLA Antigens

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to HLA-DR Antigens

Share to Inflammation

Share to Tacrolimus Binding Proteins

Share to Tumor Necrosis Factor-alpha

Share to Vascular Endothelial Growth Factors

Source

Identifiers

PMID: 19233472
DOI: 10.1016/j.molimm.2009.01.006

Genes

TNF
FKBP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Long-range linkage on chromosome 6p of VEGF, FKBP5, HLA and TNF alleles associated with transplant rejection.PMID 19233472Read ↗

Haplotype analysis on chromosome 6p of tumor necrosis factor alpha, vascular endothelial growth factor A, and interleukin-17F alleles associated with corneal transplant rejection.Semantic proximity Read ↗

Six microsatellite markers on the short arm of chromosome 6 in relation to HLA-DR3 and TNF-308A in systemic lupus erythematosus.Semantic proximity Read ↗

Linkage mapping of a novel susceptibility locus for Behçet's disease to chromosome 6p22-23.Semantic proximity Read ↗

A polymorphic microsatellite marker in the human p55 TNF receptor, CD120a.Semantic proximity Read ↗

Allograft inflammatory factor-1 and tumor necrosis factor single nucleotide polymorphisms in systemic sclerosis.Semantic proximity Read ↗

A Gambian TNF haplotype matches the European HLA-A1,B8,DR3 and Chinese HLA-A33,B58,DR3 haplotypes.Semantic proximity Read ↗

Microsatellite DNA markers from HLA region (D6S105, D6S265 and TNFa) in autochthonous Basques from Northern Navarre (Spain).Semantic proximity Read ↗

Linkage disequilibrium and age of HLA region SNPs in relation to classic HLA gene alleles within Europe.Semantic proximity Read ↗

TNFA promoter alleles--frequencies and linkage with classical HLA genes in a South German Caucasian population.Semantic proximity Read ↗

New polymorphic microsatellite markers place the haemochromatosis gene telomeric to D6S105.Semantic proximity Read ↗

Highly informative typing of the human TNF locus using six adjacent polymorphic markers.Semantic proximity Read ↗

Evidence of a non-MHC susceptibility locus in type I diabetes linked to HLA on chromosome 6.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.