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Article

Quantitative metabolomics reveals an epigenetic blueprint for iron acquisition in uropathogenic Escherichia coli.

PLoS pathogens - 1 Feb 2009

Henderson Jeffrey P, Crowley Jan R, Pinkner Jerome S, Walker Jennifer N, Tsukayama Pablo, Stamm Walter E, Hooton Thomas M, Hultgren Scott J

Abstract excerpt

Bacterial pathogens are frequently distinguished by the presence of acquired genes associated with iron acquisition. The presence of specific siderophore receptor genes, however, does not reliably predict activity of the complex protein assemblies involved in synthesis and transport of these secondary metabolites. Here, we have developed a novel quantitative metabolomic approach based on stable isotope dilution...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19229321
DOI: 10.1371/journal.ppat.1000305
PMCID: PMC2637984

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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