Article

Iron regulates contrasting toxicity of uropathogenic <i>Eschericia coli</i> in macrophages and epithelial cells

2022-05-29

Abstract excerpt

By far most urinary tract infections are caused by genetically diverse uropathogenic Escherichia coli (UPEC). Knowledge of the virulence mechanisms of UPEC is critical for drug development, but most studies focus on only a single strain of UPEC. In this study, we compared the virulence mechanisms of four antibiotic-resistant and highly pathogenic UPEC isolates in human blood monocyte-derived macrophages and a bla...

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Literature Corpus work: 638dc7dc-c38b-502f-a3dc-a4aabd803b61
DOI: 10.1101/2022.05.29.493834

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