Article
Defining a Molecular Signature for Uropathogenic versus Urocolonizing Escherichia coli: The Status of the Field and New Clinical Opportunities.
Journal of molecular biology - 14 Feb 2020
Eberly Allison R, Beebout Connor J, Carmen Tong Ching Man, Van Horn Gerald T, Green Hamilton D, Fitzgerald Madison J, De Shuvro, Apple Emily K, Schrimpe-Rutledge Alexandra C, Codreanu Simona G, Sherrod Stacy D, McLean John A, Clayton Douglass B, Stratton Charles W, Schmitz Jonathan E, Hadjifrangiskou Maria
Abstract excerpt
Urinary tract infections (UTIs) represent a major burden across the population, although key facets of their pathophysiology and host interaction remain unclear. Escherichia coli epitomizes these obstacles: this gram-negative bacterial species is the most prevalent agent of UTIs worldwide and can also colonize the urogenital tract in a phenomenon known as asymptomatic bacteriuria (ASB). Unfortunately, at the...
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