Article
Metabolic phenotyping of the Yersinia high-pathogenicity island that regulates central carbon metabolism.
The Analyst - 21 May 2015
Yan Leyu, Nie Wenna, Lv Haitao
Abstract excerpt
The high-pathogenicity island (HPI) is an important determinant of the pathogenicity of pathogenic Yersinia microbes. The HPI carries a cluster of virulence genes that chiefly account for the biosynthesis, transportation and regulation of a virulence-associated siderophore, yersiniabactin. This siderophore is also present in uropathogenic E. coli (UTI89) but not in non-uropathogenic E. coli. We sought to perform...
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