Article
Codon usage in Chlamydia trachomatis is the result of strand-specific mutational biases and a complex pattern of selective forces.
Nucleic acids research - 15 May 2000
Romero H, Zavala A, Musto H
Abstract excerpt
The patterns of synonymous codon choices of the completely sequenced genome of the bacterium Chlamydia trachomatis were analysed. We found that the most important source of variation among the genes results from whether the sequence is located on the leading or lagging strand of replication, resulting in an over representation of G or C, respectively. This can be explained by different mutational biases...
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