Article
Molecular determinants and evolutionary dynamics of wobble splicing.
Molecular biology and evolution - 1 May 2009
Lv Jianning, Yang Yun, Yin Heng, Chu Fengjiao, Wang Haitao, Zhang Wenjing, Zhang Yaozhou, Jin Yongfeng
Abstract excerpt
Alternative splicing at tandem splice sites (wobble splicing) is widespread in many species, but the mechanisms specifying the tandem sites remain poorly understood. Here, we used synaptotagmin I as a model to analyze the phylogeny of wobble splicing spanning more than 300 My of insect evolution. Phylogenetic analysis indicated that the occurrence of species-specific wobble splicing was related to synonymous...
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