Article
Quantitative analysis of wobble splicing indicates that it is not tissue specific.
Genomics - 1 Dec 2006
Tsai Kuo-Wang, Lin Wen-Chang
Abstract excerpt
Alternative splicing is an important mechanism mediating the function of genes in multicellular organisms. Recently, we discovered a new splicing-junction wobble mechanism that generates subtle alterations in mRNA by randomly selecting tandem 5' and 3' splicing-junction sites. Here we developed a sensitive approach to identify such splicing-junction wobble isoforms using polymerase chain reaction amplification...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
