Article
Androgen responsiveness of the murine beta-glucuronidase gene is associated with nuclease hypersensitivity, protein binding, and haplotype-specific sequence diversity within intron 9.
Molecular and cellular biology - 1 Nov 1991
Lund S D, Gallagher P M, Wang B, Porter S C, Ganschow R E
Abstract excerpt
The tissue specificity and genetic variability of the murine beta-glucuronidase (GUS) response to androgen provide useful markers for identifying elements which underlie this responsiveness. While GUS is expressed constitutively in all examined cell types, kidney epithelial cells uniquely exhibit...
Topics
- Androgens
- Animals
- Base Sequence
- Chromatin
- DNA
- Deoxyribonuclease I
- Gene Expression Regulation, Enzymologic
- Genes
- Genetic Variation
- Glucuronidase
- Haplotypes
- Introns
- Kidney
- Liver
- Mice
- Molecular Sequence Data