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Article

Loss of neuronatin expression is associated with promoter hypermethylation in pituitary adenoma

14 Feb 2009

Abstract excerpt

The imprinted gene, neuronatin (NNAT), is one of the most abundant transcripts in the pituitary and is thought to be involved in the development and maturation of this gland. In a recent whole-genome approach, exploiting a pituitary tumour cell line, we identified hypermethylation associated loss of NNAT. In this report, we determined the expression pattern of NNAT in individual cell types of the normal gland and...

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PMID: 19218280
DOI: 10.1677/erc-09-0008

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