Article
Molecular phenotyping of mannosyltransferases-deficient Candida albicans cells by high-resolution magic angle spinning NMR.
Journal of biochemistry - 1 Apr 2009
Maes Emmanuel, Mille Céline, Trivelli Xavier, Janbon Guilhem, Poulain Daniel, Guérardel Yann
Abstract excerpt
The yeast Candida albicans is an opportunistic pathogen that causes infections in immunocompromised individuals with a high morbidity and mortality levels. Recognition of yeasts by host cells is directly mediated by cell wall components of the yeast, including a wide range of abundantly expressed glycoconjugates. Of particular interest in C. albicans are the beta-mannosylated epitopes that show a complex...
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