Article
β-(1,3)-Glucan Unmasking in Some Candida albicans Mutants Correlates with Increases in Cell Wall Surface Roughness and Decreases in Cell Wall Elasticity.
Infection and immunity - 1 Jan 2017
Hasim Sahar, Allison David P, Retterer Scott T, Hopke Alex, Wheeler Robert T, Doktycz Mitchel J, Reynolds Todd B
Abstract excerpt
Candida albicans is among the most common human fungal pathogens, causing a broad range of infections, including life-threatening systemic infections. The cell wall of C. albicans is the interface between the fungus and the innate immune system. The cell wall is composed of an outer layer enriched in mannosylated glycoproteins (mannan) and an inner layer enriched in β-(1,3)-glucan and chitin. Detection of C....
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