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Article

Ubiquitin associated protein 1 is a risk factor for frontotemporal lobar degeneration.

Neurobiology of aging - 1 Apr 2009

Rollinson Sara, Rizzu Patrizia, Sikkink Stephen, Baker Matthew, Halliwell Nicola, Snowden Julie, Traynor Bryan J, Ruano Dina, Cairns Nigel, Rohrer Jonathan D, Mead Simon, Collinge John, Rossor Martin, Akay Ela, Guerreiro Rita, Rademakers Rosa, Morrison Karen E, Pastor Pau, Alonso Elena, Martinez-Lage Pablo, Graff-Radford Neil, Neary David, Heutink Peter, Mann David M A, Van Swieten John, Pickering-Brown Stuart M

Abstract excerpt

Frontotemporal lobar degeneration (FTLD) is now recognised as a common form of early onset dementia. Up to 40% of patients have a family history of disease demonstrating a large genetic component to its etiology. Linkage to chromosome 9p21 has recently been reported in families with this disorder...

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Identifiers

PMID: 19217189
DOI: 10.1016/j.neurobiolaging.2009.01.009
PMCID: PMC2753870

Genes

UBAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19217189-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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