Article
Development of a simple typing method for the ovine Toll-like receptor 4 gene.
Veterinary immunology and immunopathology - 15 Aug 2009
Byun S O, Zhou H, Hickford J G H
Abstract excerpt
Toll-like receptor 4 (TLR4) recognizes lipopolysaccharide (LPS) from Gram-negative bacteria, as well as a number of other ligands. Genetic variation in the TLR gene has been associated with altered immune responses to pathogens and results in variation in disease susceptibility. The objective of this work was to develop a simple and rapid genotyping system for ovine TLR4 and of a sensitivity that would allow...
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