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Article

Association of TLR2 haplotypes encoding Q650 with reduced susceptibility to ovine Johne's disease in Turkish sheep.

Scientific reports - 29 Mar 2021

Yaman Yalçın, Aymaz Ramazan, Keleş Murat, Bay Veysel, Ün Cemal, Heaton Michael P

Abstract excerpt

Ovine Johne's disease (OJD) is caused by Mycobacterium avium subsp. paratuberculosis (MAP) and carries a potential zoonotic risk for humans. Selective breeding strategies for reduced OJD susceptibility would be welcome tools in disease eradication efforts, if available. The Toll-like receptor 2 gene (TLR2) plays an important signaling role in immune response to MAP, and missense variants are associated with...

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Identifiers

PMID: 33782507
DOI: 10.1038/s41598-021-86605-4
PMCID: PMC8007707

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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