Article
Allelic variation of the ovine Toll-like receptor 4 gene.
Developmental and comparative immunology - 1 Jan 2007
Zhou Huitong, Hickford Jon G H, Fang Qian, Lin Yi-Sien
Abstract excerpt
The family of Toll-like receptors (TLRs) is responsible for recognition of pathogen-associated molecular patterns (PAMPs), and Toll-like receptor 4 (TLR4) recognizes not only exogenous ligands such as the lipopolysaccharide (LPS) of Gram-negative bacteria, but also a number of endogenous ligands. Variation in the nucleotide sequence of the ovine TLR4 gene was investigated by amplification of a fragment containing...
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