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Article

Toll-like receptor 4 (TLR4) polymorphisms in ruminants: A review of genetic associations with health, reproduction, and production traits.

Veterinary journal (London, England : 1997) - 1 Aug 2026

Abuzahra Mutasem, Destomo Alfian, Hariyono Dwi Nur Happy, Sari Aprilianna Putri Zahara Nafsina Luvita, Ibrahim Alek, Aryogi Aryogi, Romjali Endang, Handiwirawan Eko, Elieser Simon, Anggraeni Anneke, Thalib Chalid, Sutikno Sutikno, Prihandini Peni Wahyu

Abstract excerpt

Toll-like receptor 4 (TLR4), a fundamental component of the innate immune system, has been identified as a significant candidate gene for enhancing health, productivity, and reproduction in livestock. This review synthesizes and analyzes genetic association studies of TLR4 in cattle, buffaloes, sheep, and goats, assessing its significance in economically important traits. Significant evidence associates TLR4...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 42456923
DOI: 10.1016/j.tvjl.2026.106771

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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