Article
Genotyping of Toll-like receptor 4, myeloid differentiation factor 2 and CD-14 in the horse: an investigation into the influence of genetic polymorphisms on the LPS induced TNF-alpha response in equine whole blood.
Veterinary immunology and immunopathology - 15 Jun 2006
Werners A H, Bull S, Vendrig J C, Smyth T, Bosch R R, Fink-Gremmels J, Bryant C E
Abstract excerpt
The inter- and intra-species differences in the response to lipopolysaccharides (LPS) are well recognised in mammalian species. It has been hypothesized that these differences can be attributed to genetic polymorphisms in the components involved in LPS signal transduction. These components include the cluster of differentiation factor 14 (CD-14), a membrane bound protein on the surface of mononuclear cells that...
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