Article
Dual role for neural crest cells during outflow tract septation in the neural crest-deficient mutant Splotch(2H).
Journal of anatomy - 1 Feb 2009
Bradshaw Lucy, Chaudhry Bill, Hildreth Victoria, Webb Sandra, Henderson Deborah J
Abstract excerpt
Splotch(2H) (Sp(2H)) is a well-recognized mouse model of neural crest cell (NCC) deficiency that develops a spectrum of cardiac outflow tract malformations including common arterial trunk, double outlet right ventricle, ventricular septal defects and pharyngeal arch artery patterning defects, as...
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