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Article

Dual role for neural crest cells during outflow tract septation in the neural crest-deficient mutant Splotch(2H).

Journal of anatomy - 1 Feb 2009

Bradshaw Lucy, Chaudhry Bill, Hildreth Victoria, Webb Sandra, Henderson Deborah J

Abstract excerpt

Splotch(2H) (Sp(2H)) is a well-recognized mouse model of neural crest cell (NCC) deficiency that develops a spectrum of cardiac outflow tract malformations including common arterial trunk, double outlet right ventricle, ventricular septal defects and pharyngeal arch artery patterning defects, as well as defects in other neural-crest derived organ systems. These defects have been ascribed to reduced NCC in the...

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Identifiers

PMID: 19207986
DOI: 10.1111/j.1469-7580.2008.01028.x
PMCID: PMC2667882

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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