Article
Comparative validation of c-kit exon 11 mutation analysis on cytology samples and corresponding surgical resections of gastrointestinal stromal tumours.
Cytopathology : official journal of the British Society for Clinical Cytology - 1 Oct 2009
Pang N K B, Chin S Y, Nga M E, Chang A R, Ismail T-M, Omar S-S, Charlton A, Salto-Tellez M
Abstract excerpt
OBJECTIVE: Studies have shown that c-kit mutation analysis of gastrointestinal stromal tumours (GISTs) obtained by endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) can be routinely performed. We validated c-kit exon 11 mutational analysis on cell block material obtained from fine needle aspiration cytology (FNAC) for diagnostic purposes and compared it with the same analysis in formalin-fixed...
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